Optimal iodine dose for 3-dimensional multidetector-row CT angiography of the liver
| Autor: | Hiroyuki Morisaka, Katsuhiro Sano, Hironobu Sou, Tsutomu Araki, Utaroh Motosugi, Tomoaki Ichikawa, Kojiro Onohara |
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| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Portal vein Contrast Media chemistry.chemical_element Hepatic Veins Iodine Body weight Sensitivity and Specificity Imaging Three-Dimensional medicine.artery Dose group medicine Humans Radiology Nuclear Medicine and imaging Vein Aorta Dose-Response Relationship Drug medicine.diagnostic_test business.industry Reproducibility of Results Phlebography General Medicine Middle Aged Iopamidol Radiographic Image Enhancement medicine.anatomical_structure chemistry Hepatic veins Angiography Female Radiology Tomography X-Ray Computed Nuclear medicine business |
| Zdroj: | European Journal of Radiology. 81:2450-2455 |
| ISSN: | 0720-048X |
| Popis: | Purpose To clarify the optimal iodine dose of contrast material for 3-dimensional multidetector-row CT angiography (3D-MDCTA) of the venous vasculature of the liver using volume rendering technique. Materials and methods This study included 103 patients who were randomly assigned to 5 contrast-enhanced MDCT protocol groups with different body-weight-tailored doses of contrast material: 500, 600, 630, 650, and 700 mgI/kg body weight. The arterial, portal, and hepatic parenchymal phases were obtained to evaluate enhancement values of the aorta, portal vein, and hepatic vein. Visualization of the portal and hepatic veins on the volume-rendering images of 3D-MDCTA was evaluated using a 5-point grade. Dunnett's test was used to compare the mean enhancement value and mean grades of image quality (700 mgI/kg dose group was control). Results The mean enhancement values of portal and hepatic vein in the group with 500 and 600 mgI/kg were significantly lower than those of the control group. During visual assessment, a significantly lower mean grades were observed in 500 mgI/kg groups for the portal vein, and 500 and 600 mgI/kg groups for hepatic vein. There were no significant intergroup differences in mean enhancement values and visual assessment among the groups using 630 mgI/kg or more. Conclusion Iodine doses of 630 mgI/kg was recommended for 3D-MDCTA. |
| Databáze: | OpenAIRE |
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