Aqueous chlorination and ozonation studies I. Structure-toxicity correlations of phenolic compounds to Daphnia magna
| Autor: | Robert M. Carlson, Ronald Caple, Herbert L. Kopperman |
|---|---|
| Rok vydání: | 1974 |
| Předmět: |
Time Factors
Chemical Phenomena Daphnia magna Molecular Conformation chemistry.chemical_element Toxicology Medicinal chemistry Structure-Activity Relationship chemistry.chemical_compound Phenols Chlorine Animals Organic chemistry Aqueous solution biology Chemistry Physical Chemistry Biological activity General Medicine Resonance (chemistry) biology.organism_classification Kinetics Daphnia Toxicity Mathematics |
| Zdroj: | Chemico-Biological Interactions. 9:245-251 |
| ISSN: | 0009-2797 |
| DOI: | 10.1016/0009-2797(74)90015-5 |
| Popis: | A correlation showing the dependency of the observed biological activity (LC50) of a series of phenols to the free energy related terms, π, F and R (field and resonance), which are specific for each compound, has been observed for the freshwater invertebrate, Daphnia magna. A series of 14 phenols was investigated and with F and R considered to be additive terms the following correlation was obtained. Log 1/c = 0.500 π + 0.453 F + 0.636 R + 3.731 r = 0.978 In those phenols containing chlorine it was noted the toxicity increased with increased chlorine content. |
| Databáze: | OpenAIRE |
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