Diagnostic value of diffusion-weighted imaging/magnetic resonance imaging for peritoneal metastasis from malignant tumor: A systematic review and meta-analysis

Autor: Li Dong, Taisong Peng, Kuo Li
Rok vydání: 2020
Předmět:
Zdroj: Medicine
ISSN: 1536-5964
Popis: Background: Previous meta-analyses examined either multiple tools for the diagnosis of peritoneal metastases (PMs), but not diffusion-weighted imaging (DWI), or included only 1 tumor type. This study aimed to determine the summary diagnostic value of DWI/magnetic resonance imaging in determining PMs originating from various tumors. Methods: PubMed, Embase, and Cochrane library were searched for available papers up to 2019/12. Pooled estimates for sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and accuracy were calculated using random-effects models. Results: Ten studies were included and could be used to calculate the pooled sensitivity and specificity. The pooled sensitivity of DWI for PMs was 89% (95% confidence interval [CI]: 83%–93%). The pooled specificity was 86% (95% CI: 79%–91%). When considering only the retrospective studies, the pooled sensitivity of DWI for PMs was 85% (95% CI: 81%–89%). The pooled specificity was 84% (95% CI: 72%–92%). When considering only the studies about gastrointestinal tumors, the pooled sensitivity of DWI for PMs was 97% (95% CI: 68%–100%). The pooled specificity was 86% (95% CI: 69%–95%). No publication bias was observed (P = dd.27). Conclusion: DWI magnetic resonance imaging is highly sensitive and specific for the detection of PMs from various abdominal cancers.
Databáze: OpenAIRE