Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study
| Autor: | João Cardoso, Sónia Carina Silva, Sara Fernandes, Edgar Almeida, Luis Falcao, Ana Cortesão Costa, Mário Raimundo, Catarina Teixeira |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pathology
medicine.medical_specialty 030232 urology & nephrology Case Report lcsh:RC870-923 urologic and male genital diseases Serology 03 medical and health sciences Glomerulonephritis 0302 clinical medicine Mixed connective tissue disease immune system diseases medicine Rapidly progressive glomerulonephritis cardiovascular diseases Anca negative skin and connective tissue diseases Mixed Connective Tissue Disease 030203 arthritis & rheumatology biology business.industry Crescentic glomerulonephritis General Medicine lcsh:Diseases of the genitourinary system. Urology medicine.disease respiratory tract diseases Glomerulonefrite Doença Mista do Tecido Conjuntivo Pauci-immune biology.protein medicine.symptom Antibody business |
| Zdroj: | Jornal Brasileiro de Nefrologia Brazilian Journal of Nephrology, Iss 0 (2019) |
| ISSN: | 2175-8239 0101-2800 |
| Popis: | One of the most common causes of rapidly progressive glomerulonephritis (RPGN) is pauci-immune crescentic glomerulonephritis (CrGN). In the majority of cases, this condition has a positive serologic marker, the anti-neutrophil cytoplasmic antibodies (ANCAs), but in approximately 10% there are no circulating ANCAs, and this subgroup has been known as the ANCA-negative pauci-immune CrGN. RPGN can be associated with systemic diseases, but there are only few case reports describing the association with mixed connective tissue disease (MCTD). The authors report a case of ANCA-negative CrGN associated with a MCTD. |
| Databáze: | OpenAIRE |
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