Fatal Disseminated Herpes Simplex in a very premature neonate
| Autor: | Richard E. Sobonya, Ranjit I. Kylat, Joel Addams |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
lcsh:Internal medicine
Pediatrics medicine.medical_specialty viruses Intranuclear Inclusion Bodies lcsh:Medicine Autopsy Disease medicine.disease_cause Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Pathology Internal Medicine Medicine Pregnancy Complications Infectious lcsh:RC31-1245 Premature birth Pathological Premature neonate business.industry Incidence (epidemiology) lcsh:R Infant Newborn Infant Herpes Simplex 030208 emergency & critical care medicine Infant Low Birth Weight Newborn Pregnancy Complications Low birth weight Article / Autopsy Case Report Herpes simplex virus Disseminated herpes simplex Neonatal Sepsis medicine.symptom business |
| Zdroj: | Autopsy and Case Reports, Vol 8, Iss 4 (2018) Autopsy & Case Reports |
| ISSN: | 2236-1960 |
| DOI: | 10.4322/acr.2018.050 |
| Popis: | Herpes Simplex Virus infections (HSV) are ubiquitous. The neonatal HSV infection (NHSV) is rare. The incidence is estimated globally at only 10.3 per 100,000 births, but it can cause devastating disease in premature infants. Both HSV-1 and HSV-2 can be the etiologic agents in this type of vertically transmittted NHSV infection. Here we describe the pathological findings from a complete autopsy of a very low birth weight infant who succumbed to the infection despite early institution of antiviral treatment. We urge more awareness of this disease with continued surveillance; every effort should be taken to make an early diagnosis and thus prevent this devastating disease. |
| Databáze: | OpenAIRE |
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