Long term effect of phacoemulsification on intraocular pressure in patients with medically controlled primary open-angle glaucoma

Autor: Christophe Baudouin, Aymeric Bouillot, Sylvain Michée, Antoine Labbé, Loic Majstruk, Benjamin Leray, Gilles Sultan
Přispěvatelé: Gestionnaire, Hal Sorbonne Université, Hôpital Ambroise Paré [AP-HP], Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (CHNO), Consultation Marfan, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Bichat, Institut de la Vision, Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Male
Intraocular pressure
medicine.medical_specialty
Time Factors
Open angle glaucoma
genetic structures
[SDV.MHEP.CHI] Life Sciences [q-bio]/Human health and pathology/Surgery
medicine.medical_treatment
Glaucoma
[SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery
Cataract
03 medical and health sciences
Tonometry
Ocular
0302 clinical medicine
lcsh:Ophthalmology
Lens Implantation
Intraocular
Ophthalmology
medicine
Glaucoma surgery
Humans
In patient
Postoperative Period
[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs
Antihypertensive Agents
Intraocular Pressure
030304 developmental biology
Aged
Retrospective Studies
0303 health sciences
Phacoemulsification
business.industry
Retrospective cohort study
General Medicine
Cataract surgery
medicine.disease
eye diseases
3. Good health
Treatment Outcome
lcsh:RE1-994
[SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory Organs
030221 ophthalmology & optometry
Female
sense organs
business
Glaucoma
Open-Angle
Research Article
Follow-Up Studies
Zdroj: BMC Ophthalmology
BMC Ophthalmology, 2019, 19, pp.149. ⟨10.1186/s12886-019-1157-3⟩
BMC Ophthalmology, BioMed Central, 2019, 19, pp.149. ⟨10.1186/s12886-019-1157-3⟩
BMC Ophthalmology, Vol 19, Iss 1, Pp 1-7 (2019)
ISSN: 1471-2415
DOI: 10.1186/s12886-019-1157-3⟩
Popis: International audience; BACKGROUND: The effect of cataract surgery on IOP in patients with primary open-angle glaucoma (POAG) is a subject of debate. We investigated the effect of cataract surgery by phacoemulsification on intraocular pressure (IOP) in patients with medically POAG .METHODS: Seventy eyes of 40 POAG patients undergoing cataract surgery by phacoemulsification were retrospectively evaluated. All patients had their POAG medically controlled without prior glaucoma surgery. Baseline demographics and clinical characteristics were recorded. IOP and the number of glaucoma medications were evaluated before and for 1 year after cataract surgery. We analyzed IOP variations from baseline with a Student t-test for a paired sample. We used a Pearson correlation coefficient and linear regression to study the relation between IOP change from baseline and preoperative characteristics.RESULTS: One year after phacoemulsification, IOP decreased by a mean 1.15 ± 3 mmHg (6.8 ± 18.1%) (P = 0.01) and the number of glaucoma medications remained unchanged with a difference of - 0.1 ± 0.43 (P = 0.09). Higher preoperative IOP was associated with a greater IOP decrease after 1 year of follow-up (P 30 mmHg, respectively. One year after cataract surgery, 75.7% of the POAG eyes maintained the same number of glaucoma medications while 17.1% had a decrease and 7.2% of the eyes required adding glaucoma medications.CONCLUSION: Cataract surgery by phacoemulsification in eyes with medically controlled POAG resulted at 1 year in a very small IOP decrease without a change in the number of glaucoma medications. A drop in IOP should not be expected after performing phacoemulsification alone in POAG patients.
Databáze: OpenAIRE
Externí odkaz: