Influence of hyperhomocysteinemia on left ventricular diastolic function in Chinese patients with hypertension
| Autor: | L. Ruhui, Jiang Jin-Fa, M. Wenlin, X. Jiahong |
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| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Hyperhomocysteinemia China Homocysteine Diastole Comorbidity Doppler echocardiography Essential hypertension Risk Assessment Sensitivity and Specificity chemistry.chemical_compound Ventricular Dysfunction Left Internal medicine Medicine Humans Prospective cohort study medicine.diagnostic_test E/A ratio business.industry Incidence Reproducibility of Results Middle Aged medicine.disease Causality Cross-Sectional Studies chemistry Hypertension Cardiology Female Cardiology and Cardiovascular Medicine business Biomarkers |
| Zdroj: | Herz. 40(4) |
| ISSN: | 1615-6692 |
| Popis: | The aim of this study was to assess the effect of plasma homocysteine (Hcy) on left ventricular (LV) diastolic function in Chinese patients with essential hypertension. A total of 74 patients with hypertension were enrolled in the present study and were divided into two groups according to the plasma levels of Hcy: high levels of Hcy (Hhcy) group (n = 37) and control group (n = 37) with normal levels of homocysteine. The study participants consisted of 37 hypertensive patients with Hhcy and 37 hypertensive patients without Hhcy. Transthoracic Doppler echocardiography was performed to assess the LV diastolic function of the patients. The plasma level of Hcy was directly related to LV diastolic echocardiographic parameters in patients with hypertension whereby the ratio E/e’ was higher (12.7 ± 2.64 vs. 8.98 ± 1.55, p |
| Databáze: | OpenAIRE |
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