Therapeutic application of ultrasound: contrast-enhanced thrombolysis in acute ST-elevation myocardial infarction; the Sonolysis study
| Autor: | Yolande Appelman, Gerrit Veen, Jeroen Slikkerveer, Otto Kamp, N Van Royen |
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| Přispěvatelé: | Cardiology, ICaR - Heartfailure and pulmonary arterial hypertension |
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Microbubbles business.industry medicine.medical_treatment Ultrasound Therapeutic effect Percutaneous coronary intervention Thrombolysis medicine.disease Prehospital thrombolysis Myocardial infarction St elevation myocardial infarction Internal medicine medicine Cardiology Facilitated PCI cardiovascular diseases Icin business Cardiology and Cardiovascular Medicine |
| Zdroj: | Netherlands Heart Journal, 19(4), 200-205. Bohn Stafleu van Loghum Netherlands Heart Journal Slikkerveer, J, Veen, G, Appelman, Y E A, van Royen, N & Kamp, O 2011, ' Therapeutic application of ultrasound: contrast-enhanced thrombolysis in acute ST-elevation myocardial infarction; the Sonolysis study ', Netherlands Heart Journal, vol. 19, no. 4, pp. 200-205 . https://doi.org/10.1007/s12471-011-0100-x |
| ISSN: | 1568-5888 |
| DOI: | 10.1007/s12471-011-0100-x |
| Popis: | Contrast enhancement by microbubble infusion has proven its applicability in the field of diagnostic ultrasound. Recent studies also indicate a therapeutic effect of the combined use of ultrasound and microbubbles. Results from animal studies demonstrate that diagnostic ultrasound in combination with intravenous microbubbles can dissolve thrombi. So far, this effect has never been tested in patients with an acute ST-elevation myocardial infarction (STEMI). We recently launched a pilot study in acute STEMI patients to assess safety, feasibility and efficacy of the treatment in this patient group with transthoracic three-dimensional diagnostic ultrasound and intravenous microbubbles immediately after prehospital thrombolysis, but prior to primary percutaneous coronary intervention. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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