Resource Utilization Among Glaucoma Patients in the UK Treated with Beta-Blocker and Non-Beta-Blocker Adjunctive Therapy: A Retrospective Cohort Analysis
| Autor: | Ananth C. Viswanathan, Anmol Mullins, David W. Covert, Judit Banhazi, Paul McDwyer, Claudio Spera, Alberto Ferreira, Eibhlin Hudson |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Drug-Related Side Effects and Adverse Reactions Adverse outcomes medicine.drug_class Adrenergic beta-Antagonists Glaucoma Cohort Studies 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Resource utilization Humans Pharmacology (medical) CPRD 030212 general & internal medicine Beta-blocker Beta blocker Original Research Aged Retrospective Studies Aged 80 and over Adult patients business.industry Retrospective cohort study General Medicine Middle Aged medicine.disease Rheumatology United Kingdom Surgery Clinical Practice Ophthalmology 030221 ophthalmology & optometry Female business |
| Zdroj: | Advances in Therapy |
| ISSN: | 1865-8652 0741-238X |
| Popis: | Introduction Few studies have examined outcomes and potential complications among glaucoma patients who are prescribed topical beta-blockers. This study examined resource usage (number of GP visits and hospitalizations) and diagnoses of respiratory or cardiovascular conditions among glaucoma patients prescribed beta-blockers compared to patients not prescribed beta-blockers. Methods A retrospective cohort analysis was conducted using data from the UK Clinical Practice Research Datalink (CPRD) database over the period January 1, 2006 to March 31, 2014. Adult patients with at least one diagnosis of glaucoma were categorized into beta-blocker users and non-beta-blocker users. Beta-blocker users were further separated into patients that maintained beta-blocker therapy and patients that discontinued beta-blocker treatment in year 2 of the post-index period. The CPRD data was queried directly to obtain the number of GP visits, and hospitalizations were extracted by linking the CPRD and Hospital Episode Statistics (HES) patient-level data. Results In the 12 months after being prescribed beta-blockers, patients that later discontinued beta-blocker treatment had a significantly higher average number of hospitalizations than patients that maintained beta-blocker therapy and the non-beta-blocker users (p |
| Databáze: | OpenAIRE |
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