Comparison of surgery and radiotherapy in T1 and T2 glottic carcinomas
| Autor: | Jordan C. Stern, Bernard Vankemmel, Etienne Buisset, Jean-Louis Lefebvre, Jean Ton-Van, Bernard Coche-Dequeant |
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| Rok vydání: | 1991 |
| Předmět: |
Male
Glottis medicine.medical_specialty Cord medicine.medical_treatment Laryngectomy Anterior commissure Vocal Cords Radiotherapy High-Energy otorhinolaryngologic diseases Carcinoma medicine Humans Laryngeal Neoplasms Retrospective Studies Epithelioma business.industry General Medicine Middle Aged medicine.disease Survival Analysis Surgery Survival Rate Radiation therapy medicine.anatomical_structure Carcinoma Squamous Cell Cordectomy Female business |
| Zdroj: | The American Journal of Surgery. 162:337-340 |
| ISSN: | 0002-9610 |
| Popis: | We retrospectively studied 356 patients who received treatment for T1 and T2 glottic carcinomas. Two hundred and thirty patients were treated with surgery (200 by cordectomy, 15 by vertical partial laryngeetomy, and 15 by subtotal laryngectomy). Radiotherapy was used to treat 126 patients. There were 206 T1 and 24 T2 lesions in the surgically treated group and 107 T1 and 19 T2 lesions in the radiotherapy group. Sixty-four patients received radiotherapy because it was the treatment of choice (scheduled radiotherapy) and 62 patients received radiotherapy because they had medical contraindications for surgery (default radiotherapy). Actuarial survival rates at 5 years were 84% for patients who underwent surgery and 78% for patients who underwent scheduled radiotherapy. In the surgically treated group, there were 10 local recurrences in 170 patients with tumors of the true vocal cord, eight recurrences in 36 patients with anterior commissure lesions, and 6 recurrences in 24 patients with tumors extending to the arytenoid. In the scheduled radiotherapy group, there were 7 local recurrences in 38 patients with true vocal cord tumors, 6 recurrences in 20 patients with anterior commissure tumors, and 5 recurrences in 6 patients with tumors extending to the arytenoid. We conclude that survival is similar in these patients whether they receive operative treatment or scheduled radiotherapy. However, in the radiotherapy group, local recurrences were more frequent in patients with tumors extending to the arytenoid. We advocate extended functional surgery for patients with T1 and T2 glottic lesions except for those with small tumors arising from the middle third of the vocal cord. |
| Databáze: | OpenAIRE |
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