Cannabinoid hyperemesis syndrome in two French emergency departments: a prospective cohort

Autor: Julie Weiss, Baptiste Verhamme, Antoine Roch, Nicolas Simon, Romain Torrents, Pierre Lazerges, Maeva Jego, Pierre Michelet
Přispěvatelé: Dupuis, Christine, Aix-Marseille Université - Faculté des sciences médicales et paramédicales (AMU SMPM), Aix Marseille Université (AMU), Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre antipoison et de toxicovigilance (Marseille) (CAPTV Marseille), Assistance Publique - Hôpitaux de Marseille (APHM), Service de Pharmacologie Clinique [AP-HM Hôpital Ste Marguerite], Hôpital Sainte-Marguerite [CHU - APHM] (Hôpitaux Sud ), Service de réanimation-Détresses Respiratoires et Infections Sévères [Hôpital Nord - APHM] (DRIS), Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital Nord [CHU - APHM], CLINEA - Clinique de santé mentale, L'escale [Saint-Victoret, France], ORPEA Groupe, Centre d'études et de recherche sur les services de santé et la qualité de vie (CEReSS), Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hôpital Nord [CHU - APHM]-Assistance Publique - Hôpitaux de Marseille (APHM)-Aix Marseille Université (AMU)
Rok vydání: 2020
Předmět:
Zdroj: Fundamental & Clinical Pharmacology
Fundamental & Clinical Pharmacology, Wiley, 2021, 35 (1), pp.186-191. ⟨10.1111/fcp.12580⟩
Fundamental & Clinical Pharmacology, 2021, 35 (1), pp.186-191. ⟨10.1111/fcp.12580⟩
Fundamental and Clinical Pharmacology
Fundamental and Clinical Pharmacology, Wiley, 2020, Online ahead of print. ⟨10.1111/fcp.12580⟩
ISSN: 1472-8206
0767-3981
DOI: 10.1111/fcp.12580
Popis: International audience; Chronic cannabis use can be associated with uncontrollable vomiting and abdominal pain. Diagnostic criteria for cannabinoid hyperemesis syndrome (CHS) were defined in 2012 by Simonetto et al. The objectives of this study were to describe the prevalence of CHS, the patients' epidemiological characteristics, and to show the difficulties encountered in caring for these patients in emergency departments, the extent of health care and an unsuitable follow-up in general practices. A prospective cohort of patients with CHS was recruited among a target population of patients leaving the adult emergency services of the Marseille hospitals Nord and La Timone between October 2017 and July 2018, with abdominal pain syndrome of unidentified etiology. Inclusion criteria for the CHS cohort were chronic cannabis use associated with nausea and vomiting. There were 48 patients included in the CHS cohort who took cannabis daily, in a target population of 2 848 patients (i.e. 1.6%). A hot shower was the most effective symptomatic treatment in 54.2% of cases. Patients suffering from CHS spent significantly more hours in emergency departments (11 vs. 6.5), and, on average, visits were more frequent (4.9 vs. 3). 20.3% of them were hospitalized to continue pain medication. Once out of hospital, follow-up was limited, and weaning off cannabis, the only etiological treatment, was difficult to set up. Informing patients about CHS is essential, and a hot shower could be systematically proposed, thus limiting an unnecessary extent of health care. CHS is genuine, medical staff should be made aware of it in occupational training, and it should be seriously considered in health policies.
Databáze: OpenAIRE
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