Olfactory function and findings on chest computed tomography in COVID-19: is there any correlation?
| Autor: | Roberta David João De Masi, Gabriel Lucca de Oliveira Salvador, Thiago Sasso Carmona de Souza, Marcelly Botelho Soares, Lucas Resende Lucinda Mangia, Rogério Hamerschmidt, Patrícia Cristina Scarabotto |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Olfactory system 2019-20 coronavirus outbreak Pathology medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Computed tomography Correlation 03 medical and health sciences 0302 clinical medicine X ray computed medicine Humans 030223 otorhinolaryngology Lung Pandemics medicine.diagnostic_test SARS-CoV-2 business.industry COVID-19 General Medicine Middle Aged Smell Cross-Sectional Studies Otorhinolaryngology 030220 oncology & carcinogenesis Female Radiography Thoracic Tomography Tomography X-Ray Computed business Follow-Up Studies |
| Zdroj: | Acta Oto-Laryngologica |
| DOI: | 10.6084/m9.figshare.13469850 |
| Popis: | Olfactory dysfunction is frequent in COVID-19 and it might occur along with pulmonary involvement. These manifestations do not seem to share pathophysiological mechanisms, but clinical data on the subject is lacking. Aims/Objectives: This study aims to correlate the olfactory function (OF) and the radiological pulmonary involvement among in-hospital patients with COVID-19. Patients hospitalized with severe COVID-19 were consecutively recruited. They had their objective OF evaluated by the Alcohol Sniff Test and underwent a chest computed tomography (cCT). Qualitative and quantitative analyses of the cCT scans were performed by a blinded radiologist. The quantitative assessment included both the grade of involved parenchyma and the CT severity score (CT-SS). Data obtained were then compared. 57 patients were included. There was no correlation between the OF and the grade of lung involvement (p-value: .884) or the CT-SS (Pearson’s coefficient: −.111). Yet, patients with radiological findings on the cCT typical for COVID-19 did not present significantly different OF from the remaining (p-value: .193). Conclusions: Olfactory dysfunction does not correlate with the radiological lung involvement in patients hospitalized with COVID-19. There is also clinical evidence that the olfactory disorder and the pulmonary disease in COVID-19 have distinct mechanisms. Supplemental data for this article is available online at here. |
| Databáze: | OpenAIRE |
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