More than just caffeine: psychopharmacology of methylxanthine interactions with plant-derived phytochemicals

Autor: Julius Schuster, Ellen S. Mitchell
Rok vydání: 2018
Předmět:
Zdroj: Progress in neuro-psychopharmacologybiological psychiatry. 89
ISSN: 1878-4216
Popis: In general, preparations of coffee, teas, and cocoa containing high levels of polyphenols, L-theanine and other bioactive compounds selectively enhance mood and cognition effects of caffeine. This review summarizes the bioactive components of commonly consumed natural caffeine sources (e.g. guayusa, mate and camellia teas, coffee and cocoa) and analyzes the psychopharmacology of constituent phytochemicals: methylxanthines, polyphenols, and L-theanine. Acute and chronic synergistic effects of these compounds on mood and cognition are compared and discussed. Specific sets of constituent compounds such as polyphenols, theobromine and L-theanine appear to enhance mood and cognition effects of caffeine and alleviate negative psychophysiological effects of caffeine. However, more research is needed to identify optimal combinations and ratios of caffeine and phytochemicals for enhancement of cognitive performance.
Databáze: OpenAIRE