Solitary polypoid laryngeal xanthoma

Autor: Diego Collado-Martín, Beatriz Vera-Sirera, Francisco Vera-Sempere
Rok vydání: 2013
Předmět:
Zdroj: Case Reports in Otolaryngology
Case Reports in Otolaryngology, Vol 2013 (2013)
ISSN: 2090-6765
Popis: We report the case of a 51-year-old male smoker with diabetes mellitus and hyperlipidaemia and a long history of human immunodeficiency virus (HIV)/hepatitis C virus (HCV) infection treated with various antiretroviral regimes, who was referred to the otolaryngology department with progressive dysphonia. Fibre-optic laryngoscopy showed a solitary, yellowish-white pedunculated polyp on the anterior third of the left cord, with no other abnormality. Pathological analysis revealed a polypoid laryngeal xanthoma that was immunoreactive against CD68, perilipin, and adipophilin. This unusual laryngeal lesion in the clinical context of our patient suggests a possible role of antiretroviral treatment in the pathogenesis of these xanthomas.
Databáze: OpenAIRE