A clinical and echocardiographic case report of carcinoid-related valvular heart disease
| Autor: | Mustafa I. Ahmed, Ali J. Ebrahimi, Gregory Von Mering, Peter Marogil |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Heart disease Case Reports Tricuspid regurgitation 030204 cardiovascular system & hematology Neuroendocrine tumors 03 medical and health sciences 0302 clinical medicine Tricuspid Valve Insufficiency Internal medicine Case report medicine Carcinoid Heart Disease AcademicSubjects/MED00200 030212 general & internal medicine Malignant Carcinoid Syndrome Carcinoid heart disease Cardiac Imaging (Echocardiography / Cardiac MRI / Nuclear Cardiology) business.industry valvular heart disease medicine.disease Neuroendocrine neoplasms Cardiology Cardiology and Cardiovascular Medicine business Carcinoid syndrome Rare disease |
| Zdroj: | European Heart Journal: Case Reports |
| ISSN: | 2514-2119 |
| DOI: | 10.1093/ehjcr/ytaa363 |
| Popis: | Background Carcinoid syndrome is a rare disease caused by malignant neuroendocrine neoplasms. When vasoactive substances enter the systemic circulation, the triad of cutaneous flushing, bronchospasm, and diarrhoea often characterize carcinoid syndrome. Rarely, carcinoid syndrome can progress to involve the cardiac system, a condition known as carcinoid heart disease, often affecting right-sided valvular structures. Case summary Here, we present a case of malignant carcinoid syndrome with associated carcinoid heart disease in a 63-year-old female. The diagnosis of her dual regurgitant and stenotic valvular disease is detailed, with accompanying two- and three-dimensional echocardiographic images demonstrating the patient’s complex tricuspid dysfunction. Discussion Carcinoid heart disease encompasses a rare but important subset of valvular dysfunction caused by circulating vasoactive substances. Diagnosis utilizing serum studies, computed tomography scans, and echocardiography can help expedite the diagnosis and treatment of such rare conditions, and assist in the avoidance of complications. Despite its relatively well-recognized clinical presentation, carcinoid syndrome and its associated heart disease still remains a challenging condition to manage and treat, often requiring the input of several subspecialties to treat the condition appropriately. |
| Databáze: | OpenAIRE |
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