Clinical management of squamous cell carcinoma of the tongue: patients not eligible for free flaps, a systematic review of the literature
Autor: | Raffaele Rauso, Giuseppe Colella, Brigida Iorio, Davide De Cicco, Ciro Emiliano Boschetti, Gianpaolo Tartaro, Chiara Spuntarelli, Renato Franco |
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Přispěvatelé: | Colella, G., Rauso, R., De Cicco, D., Boschetti, C. E., Iorio, B., Spuntarelli, C., Franco, R., Tartaro, G. |
Rok vydání: | 2020 |
Předmět: |
squamous cell carcinoma
0301 basic medicine medicine.medical_specialty reconstruction medicine.medical_treatment Surgical Flaps scc head and neck surgery 03 medical and health sciences 0302 clinical medicine Tongue medicine cancer Humans Pharmacology (medical) Basal cell Head and neck Radiation treatment planning maxillofacial Squamous Cell Carcinoma of Head and Neck business.industry Cancer Plastic Surgery Procedures Ablation medicine.disease Tongue Neoplasms Surgery stomatognathic diseases 030104 developmental biology medicine.anatomical_structure Oncology Head and Neck Neoplasms 030220 oncology & carcinogenesis Head and neck surgery Free flap reconstruction flap business |
Zdroj: | Expert Review of Anticancer Therapy. 21:9-22 |
ISSN: | 1744-8328 1473-7140 |
DOI: | 10.1080/14737140.2021.1840359 |
Popis: | Introduction: The management of squamous cell carcinoma (SCC) of the tongue represents the most demanding treatment planning in head and neck surgery. Ablation followed by free flap reconstruction is considered the gold standard, but not all patients are suitable for this strategy. The aim of this review is to provide a comprehensive view of surgical reconstruction possibilities in patients not eligible for free flaps. Methods: Following PRISMA recommendations, a systematic literature review was conducted searching for original papers that investigated outcomes of patients treated by surgical ablation for tongue SCC followed by reconstruction with local or pedicled flaps. Selected papers were read and data extracted for qualitative analysis. Results: Twenty articles met the inclusion/exclusion criteria. The study design was case series in sixteen papers, cohort study in the remaining four. Four different local flaps (BMM, FAMM, NLIF, SMIF) and four regional flaps have been discussed in included studies (IHF, SFIF, SCM, PMMC). Conclusion: The improved anatomical knowledge makes local flaps a reliable alternative to free tissue transfer in cases requiring small-/medium-sized defects. Regional flaps still represent cornerstones in reconstruction of the tongue. Ease of execution, costs-to-benefit ratio, low-rate complications, minimal donor site morbidity represent the best advantages choosing local/regional flaps. |
Databáze: | OpenAIRE |
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