Effect of inhaled steroids on laryngeal microflora
| Autor: | Hakan Çankaya, Ahmet Arisoy, Abdülaziz Yalınkılıç, Nazim Bozan, Mehmet Fatih Garça, Yasemin Bayram, Mahfuz Turan, Selami Ekin, Rifki Ucler |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Larynx
Adult Male medicine.medical_specialty medicine.drug_class medicine.disease_cause Gastroenterology 03 medical and health sciences 0302 clinical medicine stomatognathic system Adrenal Cortex Hormones Internal medicine Vallecula Administration Inhalation medicine Humans Prospective Studies Patient group 030223 otorhinolaryngology Candida albicans biology Streptococcus business.industry Pharynx General Medicine Middle Aged biology.organism_classification Surgery stomatognathic diseases medicine.anatomical_structure 030228 respiratory system Otorhinolaryngology Microorganism classification Corticosteroid Female sense organs business |
| Popis: | Conclusions As is known, this study is the first study to evaluate the effect of inhaled steroids on laryngeal microflora. The data support that ICS usage causes changes in the larynx microflora. Purpose The aim of this study was to determine the alteration in larynx microbial flora of the patients treated with ICS comparing the culture results of a control group. In addition, laryngeal microflora was compared to the smears obtained from the vallecula and pharynx. Materials and methods The study included 39 patients (mean age = 45.56 ± 12.76 years) who had been using a corticosteroid inhaler and control group consisting of 27 persons (mean age = 43.07 ± 13.23 years). Culture samples were obtained from the pharynx, larynx, and vallecula in the patient and control groups, and they were evaluated in the microbiology laboratory. Obtained culture results were named by the same microbiologist according to the basic microorganism classification method. Results Coagulase-negative staphylococci (CNS), Streptococcus viridians (VGS) and candida albicans were detected to grow significantly more in the patient group in all three anatomic localizations compared to the control group. Neisseria spp, basillus spp, and Non-viridans alpha-hemolytic streptococcus were detected to grow significantly more in the control group in all three anatomic localizations compared to the patient group. |
| Databáze: | OpenAIRE |
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