Iridium-192 afterloaded implant in the retreatment of head and neck cancers

Autor: A.M. Nisar Syed, David Neblett, Frederick W. George, Bernard H. Feder
Rok vydání: 1978
Předmět:
Zdroj: The British Journal of Radiology. 51:814-820
ISSN: 1748-880X
0007-1285
DOI: 10.1259/0007-1285-51-610-814
Popis: Retreatment of persistent (or “recurrent”) carcinoma of the head and neck by means of after-loading 192Ir techniques may prove quite satisfactory. A total of 64 patients were retreated by these techniques from February, 1974 to October, 1975 at the Los Angeles County—University of Southern California Medical Center and the Southern California Cancer Center. Follow-up periods, averaging only 24 months (18 to 36 months), are too short for statistically significant evaluation of survival, but the “response rate” has been gratifying. Only 11 of our 64 patients (17%) have shown no satisfactory response to re-irradiation by interstitial implant. Thirty-one of the 64 patients (49%) have had local control with “good palliation”. Twenty-two of the 64 (34%) had at least 50% regression of tumour with “fair” palliation. Thus 83% have had satisfactory response to retreatment. A considerable number of these have survived to the date of this report. Whereas 36 of the 64 (56%) are now dead, 28 of the 64 otherwis...
Databáze: OpenAIRE