Chemokines: Their role in rheumatoid arthritis
| Autor: | Clarissa E. Vergunst, Paul P. Tak |
|---|---|
| Přispěvatelé: | Other departments, Amsterdam institute for Infection and Immunity, Clinical Immunology and Rheumatology |
| Rok vydání: | 2005 |
| Předmět: |
CCR1
Immunity Cellular medicine.medical_specialty Chemokine biology business.industry medicine.disease Rheumatology Arthritis Rheumatoid On cells Immune system Internal medicine Rheumatoid arthritis Immunology medicine biology.protein Animals Humans Receptors Chemokine Chemokines business Receptor Homeostasis |
| Zdroj: | Current rheumatology reports, 7(5), 382-388. Current Science, Inc. |
| ISSN: | 1534-6307 1523-3774 |
| Popis: | Chemokines are small proteins that can act on cells that express matching receptors. They are best known for their role in migration of cells, especially immune cells. Chemo-kine/ chemokine-receptor pairs are often functionally cate-gorized into three groups: inflammatory, homeostatic, and angiogenic/angiostatic, although functions sometimes over-lap. Interfering with the interaction between chemokines and their receptors is currently under investigation as a therapeutic strategy in rheumatoid arthritis. |
| Databáze: | OpenAIRE |
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