Management of familial benign chronic pemphigus
| Autor: | Fleta N. Bray, Jessica Cervantes, Harleen Arora, Leyre A Falto Aizpurua |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Atp2c1 gene business.industry Acantholysis Treatment options Review Dermatology Intertriginous Disease medicine.disease Hailey–Hailey disease corticosteroids laser Benign Chronic Pemphigus 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis familial benign chronic pemphigus medicine dermabrasion business Benign familial chronic pemphigus |
| Zdroj: | Clinical, Cosmetic and Investigational Dermatology |
| ISSN: | 1178-7015 |
| DOI: | 10.2147/ccid.s89483 |
| Popis: | Benign familial chronic pemphigus or Hailey–Hailey disease is caused by an autosomal dominant mutation in the ATP2C1 gene leading to suprabasilar acantholysis. The disease most commonly affects intertriginous areas symmetrically. The chronic nature of the disease and multiple recurrences make the disease bothersome for patients and a treatment challenge for physicians. Treatments include topical and/or systemic agents and surgery including laser. This review summarizes the available treatment options. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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