Effects of high-whey-protein intake and resistance training on renal, bone and metabolic parameters in rats

Autor: Pilar Aranda Ramírez, Elena Nebot, Jesús M. Porres, María López-Jurado, Virginia A. Aparicio, José M. Heredia, Francisco B. Ortega
Rok vydání: 2010
Předmět:
Zdroj: The British journal of nutrition. 105(6)
ISSN: 1475-2662
Popis: Consumption of high-protein (HP) diets is postulated to exert a negative influence on bone and renal health. However, no conclusive evidence has been presented related to this issue or to the potential protective action of resistance training on HP-induced systemic effects. We examined the effects of HP diet consumption on food intake, body-weight gain, body composition, and renal, bone and metabolic parameters of rats performing resistance training. A total of ninety-six adult male Wistar rats were randomly distributed in twelve experimental groups (n8): normal-protein (10 %) or HP (45 %) diets, with or without resistance training, killed for experimental periods of 1, 2 or 3 months. Diets were based on a commercial whey protein hydrolysate. Consumption of HP diets and resistance training significantly affected food intake, body weight and body composition, as well as the plasma levels of total cholesterol, HDL-cholesterol and TAG. The buffering action of resistance training on such diet-induced alterations was especially evident in the levels of plasma TAG. Consumption of HP diets led to a considerable increase in kidney weight, urinary volume and acidity, as well as in the urinary excretion of Ca, with a parallel reduction in the urinary excretion of citrate (P
Databáze: OpenAIRE