Supplementary Data from Measurement of Tumor Antioxidant Capacity and Prediction of Chemotherapy Resistance in Preclinical Models of Ovarian Cancer by Positron Emission Tomography

Autor: Timothy H. Witney, Daniel Hochhauser, Erik Årstad, Mark F. Lythgoe, Norman Koglin, Tong Zhang, Kerstin Sander, Oliver D. K. Maddocks, Raul Pereira, Matthias Glaser, Thibault Gendron, Patrick N. McCormick, Hannah E. Greenwood
Rok vydání: 2023
Popis: Supplementary Figures 1 - 6. Fig. S1 shows the ability of PEO1, PEO4 and PEO6 cells to form colonies following cisplatin treatment; Fig. S2 demonstrates that [18F]FDG uptake in A2780 cells is unrelated to drug resistance; Fig. S3 examines the expression of key ABC transporters; Fig. S4 provides representative PET images of mice bearing A2780 WT and A2780 DoxR tumors; Fig. S5 quantifies the [18F]FSPG tumor-to-background ratio in WT and DoxR tumor-bearing mice; and Fig. S6 illustrates [18F]FSPG DoxR tumor retention after doxil treatment of mice.
Databáze: OpenAIRE