Assessment of toxicological profiles of the municipal wastewater effluents using chemical analyses and bioassays

Autor: Branka Pivčević, Roko Zaja, Marta Popović, Ivan Senta, Tvrtko Smital, Knut Erik Tollefsen, Senka Terzić, Iva Mikac, Kevin V. Thomas, Marijan Ahel
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Croatia
Health
Toxicology and Mutagenesis
0211 other engineering and technologies
Silica Gel
02 engineering and technology
Chemical Fractionation
010501 environmental sciences
Waste Disposal
Fluid
01 natural sciences
Gas Chromatography-Mass Spectrometry
Mass Spectrometry
Tandem Mass Spectrometry
Liquid chromatography–mass spectrometry
Cytochrome P-450 CYP1A1
Water Pollution
Chemical
Bioassay
organic contaminants
wastewater
GC/MS
LC/MS
bioassays
identification
Cities
Chronic toxicity
Effluent
0105 earth and related environmental sciences
021110 strategic
defence & security studies
Chromatography
Sewage
Chemistry
Solid Phase Extraction
Public Health
Environmental and Occupational Health
General Medicine
Pollution
Drug Resistance
Multiple
6. Clean water
Wastewater
13. Climate action
Environmental chemistry
Environmental Science
Biological Assay
Sewage treatment
Gas chromatography–mass spectrometry
Water Pollutants
Chemical
Chromatography
Liquid
Environmental Monitoring
Waste disposal
Zdroj: Ecotoxicology and Environmental Safety
DOI: 10.1016/j.ecoenv.2010.11.010
Popis: The hazardous chemical contamination of untreated wastewater and secondary effluent from the wastewater treatment plant (WWTP) of the city of Zagreb, Croatia was comprehensively characterized using large-volume solid-phase extraction (SPE) and silica gel fractionation, followed by a detailed analysis of the resulting extracts by a combination of chemical and bioassay methods. Over 100 individual contaminants or closely related-contaminant groups were identified by high-resolution gas chromatography/mass spectrometry (GC/MS) and liquid chromatography/quadrupole time-of-flight mass spectrometry (LC-QTOF). Ecotoxicity profiling of the investigated samples, including cytotoxicity, chronic toxicity and EROD activity; inhibition of the multixenobiotic resistance (MXR), genotoxicicity and estrogenic potential, revealed the most significant contribution of toxic compounds to be present in polar fractions. Wastewater treatment using conventional activated sludge process reduced the initial toxicity of raw wastewater to various extents, ranging from 28% for algal toxicity to 73.2% for an estrogenic activity. The most efficient toxicity removal was observed for the polar compounds.
Databáze: OpenAIRE
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