Association of insomnia with mania in Lebanese patients with bipolar disorder
| Autor: | Chadia Haddad, L. Ghanem, Jocelyne Azar, Sahar Obeid, Souheil Hallit, Fouad Tahan, Francois Kazour, A. Chok |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Bipolar Disorder business.industry Quality of sleep medicine.disease behavioral disciplines and activities 030227 psychiatry Hospitalization Mania 03 medical and health sciences Psychiatry and Mental health 0302 clinical medicine Arts and Humanities (miscellaneous) Sleep Initiation and Maintenance Disorders Internal medicine mental disorders medicine Insomnia Humans In patient Bipolar disorder medicine.symptom business After treatment |
| Zdroj: | L'Encéphale. 47:314-318 |
| ISSN: | 0013-7006 |
| DOI: | 10.1016/j.encep.2020.09.008 |
| Popis: | To assess: (1) the association between insomnia experienced at admission, sociodemographic and other patients' characteristics and mania; and (2) the variation of insomnia and mania before and after treatment in bipolar patients with manic episodes (type I).Sixty-two patients were interviewed shortly after their admission to the hospital (after 3 to 5 days). The current symptoms experienced by the patients were assessed upon admission and again at discharge from the hospital.A poorer quality of sleep (higher PSQI scores) (Beta=0.590) was significantly associated with higher mania, whereas the intake of SSRIs (Beta=-5.952) and TCAs (Beta=-8.181) was significantly associated with lower mania. Furthermore, highly significant reductions were reported in the PSQI scores (4.96 vs. 2.75, P0.001), ISI scores (8.30 vs. 3.45, P0.001) and YMRS scores (8.60 vs. 3.06, P0.001) between admission to and discharge from the hospital.Insomnia in patients with bipolar disorder type I is associated with mania, with a significant reduction of sleep problems seen during a period of approximately 20 days of hospitalization. Further longitudinal studies are needed to confirm the validity of our results and identify the causes. In the meantime, this research recommends a strategy to improve sleeplessness experienced during inter-episode phases may be helpful in preventing manic episodes in BD. |
| Databáze: | OpenAIRE |
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