Salvage Re-irradiation with Intensity-modulated Radiotherapy, Chemotherapy Combined with Hyperthermia for Local Recurrence of Nasopharyngeal Carcinoma After Chemoradiotherapy
| Autor: | Tetsuro Wakasugi, Takayuki Ohguri, Yukunori Korogi, Hideaki Suzuki, Sota Nakahara, Takahiro Morisaki, Sho Kakinouchi, Katsuya Yahara, Hirohide Itamura |
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| Rok vydání: | 2021 |
| Předmět: |
Re-Irradiation
Hyperthermia medicine.medical_specialty medicine.medical_treatment Radioresistance medicine Humans Retrospective Studies Chemotherapy Nasopharyngeal Carcinoma business.industry Public Health Environmental and Occupational Health Cancer Nasopharyngeal Neoplasms General Medicine Chemoradiotherapy medicine.disease Radiation therapy Nasopharyngeal carcinoma Radiology Radiotherapy Intensity-Modulated Neoplasm Recurrence Local business |
| Zdroj: | Journal of UOEH. 43(3) |
| ISSN: | 0387-821X |
| Popis: | A sufficient dose of radiation is difficult to administer in re-irradiation for local recurrence of cancer after radiotherapy because of the dose limitation to organs at risk. Re-irradiation cases also include radioresistant tumors that are difficult to control locally, and their prognosis is poor in general. The effect of re-irradiation using intensity-modulated radiotherapy (IMRT) has recently been reported to significantly reduce the dose to organs at risk, and the efficacy of hyperthermia has been reported for radioresistant tumors. We report a case of local recurrence after concurrent chemoradiotherapy treated with salvage re-irradiation using IMRT and chemotherapy combined with hyperthermia in a patient with nasopharyngeal carcinoma, and include a discussion of the literature. |
| Databáze: | OpenAIRE |
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