Successful Nicotine Intake in Medical Assisted Use of E-Cigarettes: A Pilot Study
| Autor: | Silvia Graziano, Giuseppina Massaro, Simona Pichini, Manuela Pellegrini, Roberta Pacifici, Fabio Beatrice |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Nicotine Adolescent Health Toxicology and Mutagenesis medicine.medical_treatment lcsh:Medicine Craving Pilot Projects Electronic Nicotine Delivery Systems law.invention smoking cigarette chemistry.chemical_compound Young Adult law medicine Humans cotinine Smoking Reduction Tobacco harm reduction trans-3’-hydroxycotinine Carbon Monoxide business.industry Communication lcsh:R Smoking Public Health Environmental and Occupational Health Tobacco Use Disorder Middle Aged Surgery electronic cigarette chemistry Emergency medicine Smoking cessation Female Smoking Cessation medicine.symptom Cotinine Breath carbon monoxide business Electronic cigarette Biomarkers medicine.drug tobacco harm reduction |
| Zdroj: | International Journal of Environmental Research and Public Health International Journal of Environmental Research and Public Health, Vol 12, Iss 7, Pp 7638-7646 (2015) |
| ISSN: | 1660-4601 |
| Popis: | The electronic cigarette (e-cig) has gained popularity as an aid in smoking cessation programs mainly because it maintains the gestures and rituals of tobacco smoking. However, it has been shown in inexperienced e-cig users that ineffective nicotine delivery can cause tobacco craving that could be responsible for unsuccessful smoking reduction/cessation. Moreover, the incorrect use of an e-cig could also led to potential nicotine overdosage and intoxication. Medically assisted training on the proper use of an e-cig plus behavioral support for tobacco dependence could be a pivotal step in avoiding both issues. We performed an eight-month pilot study of adult smokers who started e-cig use after receiving a multi-component medically assisted training program with monitoring of nicotine intake as a biomarker of correct e-cig use. Participants were tested during follow-up for breath carbon monoxide (CO), plasma cotinine and trans-3’-hydroxycotinine, and number of tobacco cigarettes smoked. At the end of the first, fourth, and eighth month of follow-up, 91.1, 73.5, and 76.5% of participants respectively were e-cig users (‘only e-cig’ and ‘dual users’). They showed no significant variation in plasma cotinine and trans-3’-hydroxycotinine with respect to the start of the study when they smoked only tobacco cigarettes, but a significant reduction in breath CO. The proposed medically assisted training program of e-cig use led to a successful nicotine intake, lack of typical cigarette craving and overdosage symptoms and a significant decrease in the biomarker of cigarette combustion products. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|