Maternal early life maltreatment and psychopathology affect the next generation: Alterations in post-awakening cortisol levels of primary school-aged children
| Autor: | Anna-Lena Zietlow, Anna Fuchs, Johannes Zimmermann, Karen Hillmann, Corinne Neukel, Eva Möhler, Sabine C. Herpertz, Michael Kaess, Katja Bertsch |
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| Rok vydání: | 2019 |
| Předmět: |
Hypothalamo-Hypophyseal System
Hydrocortisone Poison control Pituitary-Adrenal System Affect (psychology) Suicide prevention Occupational safety and health 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine Developmental Neuroscience Injury prevention Developmental and Educational Psychology Medicine Humans 0501 psychology and cognitive sciences Child Schools business.industry Mental Disorders 05 social sciences Human factors and ergonomics Maternal sensitivity business 030217 neurology & neurosurgery 050104 developmental & child psychology Developmental Biology Psychopathology Clinical psychology |
| Zdroj: | Developmental psychobiologyREFERENCES. 63(1) |
| ISSN: | 1098-2302 |
| Popis: | Early life maltreatment (ELM) has severe and lasting effects on the individual, which might also impact the next generation. On an endocrine level, the hypothalamus-pituitary-adrenal axis has been suggested to play an important role in the interplay between ELM and the development of mental disorders. Several studies have revealed that maternal post-awakening cortisol concentration, maternal sensitivity, maternal ELM and psychopathology are associated with children's cortisol levels. We investigated the post-awakening cortisol concentrations in 6- to 11-year-old children (N = 53) whose mothers either had experienced ELM and had developed a lifetime mental disorder (N = 15 ELM and disorder group), had experienced ELM without developing a mental disorder (N = 12 ELM-only group), or had neither experienced ELM nor developed a mental disorder (N = 26 HC-group). Furthermore, we assessed maternal post-awakening cortisol concentrations, maternal psychopathology, and sensitivity. Multilevel analysis revealed higher cortisol at awakening (S1) levels in children of mothers with ELM and disorder. Maternal cortisol at awakening (S1) also predicted the child's cortisol at awakening (S1), and no effect of maternal sensitivity could be found. The current results replicate an attunement of cortisol levels (S1) between mothers and children and suggest an association between the children's endocrine stress system and maternal factors such as ELM and psychopathology. |
| Databáze: | OpenAIRE |
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