Early treatment with tolvaptan improves diuretic response in acute heart failure with renal dysfunction

Autor: Peter van der Meer, Satoshi Yamaguchi, Makoto Noda, Toshihiko Nishioka, Seiji Fukamizu, Nobuyuki Kagiyama, Yuya Matsue, Yuichi Ono, Makoto Suzuki, Yuko Onishi, Takeshi Kitai, Jozine M. ter Maaten, Kevin Damman, Adriaan A. Voors, Yasuhiro Satoh, Kaoru Sugi, Hiroyuki Fujii, Kazuki Yoshida, Steven R. Goldsmith, Sho Torii
Přispěvatelé: Cardiovascular Centre (CVC), Restoring Organ Function by Means of Regenerative Medicine (REGENERATE)
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Male
Time Factors
medicine.medical_treatment
Tolvaptan
Worsening renal function
AN ANALYSIS
030204 cardiovascular system & hematology
NESIRITIDE
THERAPY
0302 clinical medicine
LOOP DIURETICS
030212 general & internal medicine
Renal Insufficiency
Diuretics
Aged
80 and over

OUTCOMES
Furosemide
General Medicine
TRIALS
Treatment Outcome
Acute Disease
Injections
Intravenous

Cardiology
Female
Cardiology and Cardiovascular Medicine
Antidiuretic Hormone Receptor Antagonists
medicine.drug
Glomerular Filtration Rate
Hyponatremia
medicine.medical_specialty
Randomization
CLINICAL EFFECTIVENESS
Renal function
FUROSEMIDE
03 medical and health sciences
Internal medicine
medicine
Humans
Aged
Retrospective Studies
Nesiritide
Heart Failure
Original Paper
Dose-Response Relationship
Drug

business.industry
Acute heart failure
Benzazepines
medicine.disease
Diuresis
Blood pressure
Heart failure
Dyspnea relief
RELAX-AHF
Diuretic
business
RESISTANCE
Follow-Up Studies
Zdroj: Clinical Research in Cardiology
Clinical Research in Cardiology, 106(10), 802-812. SPRINGER HEIDELBERG
ISSN: 1861-0692
1861-0684
Popis: Background Poor response to diuretics is associated with worse prognosis in patients with acute heart failure (AHF). We hypothesized that treatment with tolvaptan improves diuretic response in patients with AHF. Methods We performed a secondary analysis of the AQUAMARINE open-label randomized study in which a total of 217 AHF patients with renal impairment (eGFR
Databáze: OpenAIRE