Comparison of Micro-US and Multiparametric MRI for Prostate Cancer Detection in Biopsy-Naive Men

Autor:	Sangeet Ghai, Nathan Perlis, Chantal Atallah, Sarah Jokhu, Kateri Corr, Katherine Lajkosz, Peter F. Incze, Alexandre R. Zlotta, Umesh Jain, Hannah Fleming, Antonio Finelli, Theodorus H. van der Kwast, Masoom A. Haider
Rok vydání:	2022
Předmět:	Male Image-Guided Biopsy Prostate Humans Prostatic Neoplasms Radiology Nuclear Medicine and imaging Prospective Studies Middle Aged Multiparametric Magnetic Resonance Imaging Magnetic Resonance Imaging Aged
Zdroj:	Radiology. 305:390-398
ISSN:	1527-1315 0033-8419
DOI:	10.1148/radiol.212163
Popis:	Background Multiparametric MRI has led to increased detection of clinically significant prostate cancer (csPCa). Micro-US is being investigated for csPCa detection. Purpose To compare multiparametric MRI and micro-US in detecting csPCa (grade group ≥2) and to determine the proportion of MRI nodules visible at micro-US for real-time targeted biopsy. Materials and methods This prospective, single-center trial enrolled biopsy-naive men with suspected prostate cancer (PCa) between May 2019 and September 2020. All patients underwent multiparametric MRI followed by micro-US; findings at both were interpreted in a blinded fashion, followed by targeted biopsy and nontargeted systematic biopsy using micro-US. Proportions were compared using the exact McNemar test. The differences in proportions were calculated. Results Ninety-four men (median age, 61 years; IQR, 57-68 years) were included. MRI- and micro-US-targeted biopsy depicted csPCa in 37 (39%) and 33 (35%) of the 94 men, respectively (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514504dbdc11bd05589446229a6c35ea https://doi.org/10.1148/radiol.212163 Zobrazit plný text záznamu