Structural and Functional Basis of Chronic Pelvic Pain Syndrome during Combined Chronic Cystitis and Adenomyosis
| Autor: | A. K. Pichigina, N. V. Shelkovnikova, E. L. Lushnikova, A. I. Neimark |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Pelvic pain syndrome medicine.medical_specialty media_common.quotation_subject Pelvic Pain Gastroenterology Urination General Biochemistry Genetics and Molecular Biology Internal medicine Cystitis medicine Humans Adenomyosis Urothelium Urogenital disorders media_common Pain syndrome business.industry General Medicine Chronic Cystitis Middle Aged medicine.disease Uterine walls Chronic Disease Female business |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 158:742-747 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-015-2852-6 |
| Popis: | Comprehensive clinical and morphological examination of 60 female patients with chronic pelvic pain syndrome after combined chronic cystitis and adenomyosis was carried out. In all patients, the complex urodynamic examination revealed various disturbances of urination and stasis-like abnormalities of circulation in vesical and uterine walls. The pathomorphological peculiarities of the urogenital disorders during combination of adenomyosis and cystitis (of the combined proliferative and erosive/destructive type) is manifested by more pronounced destructive and inflammatory changes in urothelium characterized by the formation of superficial and deep erosions as well as by association of erosive/destructive damages to the urothelium with proliferative and metaplastic changes. Combined treatment of chronic cystitides and adenomyosis eliminated the destructive and inflammatory alterations in the vesical mucosa in 70 and 93% female patients, respectively (the corresponding values after basic therapy were 60 and 77%), and pronouncedly ameliorated pain syndrome. |
| Databáze: | OpenAIRE |
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