Management of aortic arch interruption with prostaglandin E1 infusion and microporous expanded polytetrafluoroethylene grafts
| Autor: | Timothy J. Gardner, J.Michel A. Roland, James S. Donahoo, Anthony F. Cutilletta, Langford Kidd, Kenneth G. Zahka |
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| Rok vydání: | 1980 |
| Předmět: |
Aortic arch
Cardiac Catheterization medicine.medical_specialty Time Factors Oliguria Aorta Thoracic Expanded polytetrafluoroethylene Aortic arch interruption chemistry.chemical_compound Postoperative Complications Internal medicine medicine.artery medicine Humans Infusions Parenteral Prostaglandin E1 Adverse effect Polytetrafluoroethylene Polytetrafluoroethylene graft business.industry Prostaglandins E Mortality rate Infant Newborn Metabolic acidosis Prostheses and Implants Hydrogen-Ion Concentration medicine.disease Surgery chemistry Anesthesia Cardiology Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | The American Journal of Cardiology. 46:1001-1005 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/0002-9149(80)90358-6 |
| Popis: | Prostaglandin E1 infusion and a microporous expanded polytetrafluoroethylene graft were used in the management of eight infants, all less than 4 days old, with interruption of the aortic arch. Five of the six infants receiving prostaglandin E1 responded dramatically to this therapy, with return of lower limb pulses and lessening of metabolic acidosis. There were no adverse effects attributable to the prostaglandin E1 infusion. Seven infants subsequently underwent aortic reconstruction with a polytetrafluoroethylene graft. There were no operative deaths, and in up to 3 years of follow-up of these patients, graft obstruction occurred in only one patient and this graft was successfully revised. The long-term mortality rate was high (62 percent); all deaths but one were attributable either to the palliation or to the total correction of the associated cardiac malformations. |
| Databáze: | OpenAIRE |
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