Stage D prostatic carcinoma Survival rate in relapsed patients following new forms of palliation

Autor: Claude Merrin, Arnold Mittelman, K. Welvaart, Gerald P. Murphy
Rok vydání: 1974
Předmět:
Zdroj: Urology. 4:283-286
ISSN: 0090-4295
DOI: 10.1016/0090-4295(74)90378-1
Popis: Patients with progressive Stage D carcinoma of the prostate resistant to conventional endocrine therapy were evaluated for their symptomatic response to bilateral adrenalectomy, hypophysectomy, combination hypophysectomy and adrenalectomy, or chemotherapy with a new oral steroidal-alkylating agent, Estracyt (estramustine phosphate). Good, long-term palliative responses were achieved with bilateral adrenalectomy, hypophysectomy, and Estracyt. Because of its ease of administration, effectiveness, and lack of toxicity, oral Estracyt may be considered the method of choice in some cases for failures following conventional hormonal therapy.
Databáze: OpenAIRE