Headache associated with COVID-19: Frequency, characteristics and association with anosmia and ageusia

Autor:	João Eudes Magalhães, Pedro Augusto Sampaio Rocha-Filho
Rok vydání:	2020
Předmět:	Adult Male 2019-20 coronavirus outbreak medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Pneumonia Viral Anosmia Betacoronavirus Olfaction Disorders 03 medical and health sciences 0302 clinical medicine medicine Humans In patient ageusia Pandemics Special Section Articles Aged 030304 developmental biology 0303 health sciences Headache epidemiology SARS-CoV-2 business.industry Headache COVID-19 General Medicine Middle Aged Ageusia Dermatology Cross-Sectional Studies Female Neurology (clinical) medicine.symptom Coronavirus Infections business anosmia 030217 neurology & neurosurgery
Zdroj:	Cephalalgia
ISSN:	1468-2982 0333-1024
Popis:	ObjectivesTo assess the frequency and characteristics of headache in patients with COVID-19 and whether there is an association between headache and anosmia and ageusia.MethodsThis was a cross-sectional study. Consecutive patients admitted to hospital with COVID-19, confirmed by reverse transcription polymerase chain reaction (RT-PCR) technique, were assessed by neurologists.ResultsSeventy-three patients were included in the study, 63% were male; the median age was 58 years (IQR: 47–66). Forty-seven patients (64.4%) reported headaches, which had most frequently begun on the first day of symptoms, were bilateral (94%), presenting severe intensity (53%) and a migraine phenotype (51%). Twelve patients (16.4%) presented with headache triggered by coughing. Eleven (15%) patients reported a continuous headache. Twenty-eight patients (38.4%) presented with anosmia and 29 (39.7%) with ageusia. Patients who reported hyposmia/anosmia and/or hypogeusia/ageusia experienced headache more frequently than those without these symptoms (OR: 5.39; 95% CI:1.66–17.45; logistic regression). Patients with anosmia and ageusia presented headache associated with phonophobia more often compared to those with headache without these complaints (Chi-square test; p ConclusionHeadaches associated with COVID-19 are frequent, are generally severe, diffuse, present a migraine phenotype and are associated with anosmia and ageusia.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51246eeb34c7fc2b6d327376cc5e852e https://doi.org/10.1177/0333102420966770 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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