Unveiling novel forms of hippocampal synaptic plasticity with microelectrode arrays

Autor: Michel Vignes, Fabien Lanté, Nadine Crouzin
Přispěvatelé: Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Male
MESH: Microelectrodes
Patch-Clamp Techniques
MESH: Hippocampus
MESH: Neurons
Hippocampus
Nonsynaptic plasticity
MESH: Rats
Sprague-Dawley
MESH: Animals
Newborn
Membrane Potentials
MESH: Synapses
Rats
Sprague-Dawley
0302 clinical medicine
Cyclic AMP
Excitatory Amino Acid Agonists
MESH: Animals
MESH: Neuronal Plasticity
Enzyme Inhibitors
MESH: Brain Mapping
MESH: Cyclic AMP
Neurons
0303 health sciences
Brain Mapping
Synaptic scaling
Neuronal Plasticity
Chemistry
General Neuroscience
Age Factors
MESH: Electric Stimulation
Long-term potentiation
General Medicine
MESH: Excitatory Amino Acid Antagonists
MESH: Enzyme Inhibitors
NMDA receptor
Female
[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]
Sodium Channel Blockers
MESH: Rats
Models
Neurological
Tetrodotoxin
In Vitro Techniques
MESH: Mitogen-Activated Protein Kinase Kinases
03 medical and health sciences
MESH: Models
Neurological
Synaptic augmentation
MESH: Patch-Clamp Techniques
MESH: Dose-Response Relationship
Radiation
Animals
MESH: Membrane Potentials
030304 developmental biology
Mitogen-Activated Protein Kinase Kinases
MESH: Age Factors
Dose-Response Relationship
Radiation
Electric Stimulation
MESH: Tetrodotoxin
MESH: Male
Rats
Synaptic fatigue
Animals
Newborn
Metabotropic glutamate receptor
MESH: Sodium Channel Blockers
Synapses
MESH: Excitatory Amino Acid Agonists
Neuroscience
Excitatory Amino Acid Antagonists
Microelectrodes
MESH: Female
030217 neurology & neurosurgery
Zdroj: Journal of Integrative Neuroscience
Journal of Integrative Neuroscience, World Scientific Publishing, 2008, 7 (2), pp.249-70. ⟨10.1142/s0219635208001800⟩
ISSN: 0219-6352
Popis: International audience; In this report, we elucidate by use of microelectrode arrays novel forms of long-term depression and potentiation in the hippocampus which are triggered by low frequency afferent stimulation and which rely on the activation of metabotropic glutamate receptor of the fifth subtype (mGlu5 receptor).
Databáze: OpenAIRE
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