Acute and chronic brucellosis eleven-year audit from a tertiary hospital in Armenia
| Autor: | Gayane Poghosyan, Vladimir Shekoyan, Katrina Hann, Samvel Gasparyan, Lilit Sargsyan, Diana Petrosyan, Vladimir Davidyants, Karapet Davtyan |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Multivariate analysis Referral Adolescent Disease Microbiology Brucellosis Tertiary Care Centers Young Adult Virology medicine Humans Infectious disease (athletes) Aged Retrospective Studies Aged 80 and over business.industry Incidence (epidemiology) Medical record Incidence Age Factors Retrospective cohort study General Medicine Armenia Middle Aged medicine.disease Infectious Diseases Parasitology Female Topography Medical business |
| Zdroj: | Journal of infection in developing countries. 13(5.1) |
| ISSN: | 1972-2680 |
| Popis: | Introduction: The incidence of brucellosis in Armenia in 2010 was twice as high as in other countries of the Caucasian region and has almost doubled over the last three decades. This study aimed to investigate factors associated with acute or chronic forms of presentation of human brucellosis. Methodology: Retrospective study using data from medical records of 455 patients hospitalized for the first time at the Nork Republican Infectious Disease Referral Hospital in Yerevan, Armenia between the years 2006 and 2016. We undertook descriptive analysis of cases, compared acute and chronic cases, and identified factors associated with acute and chronic cases using regression. Results: The majority of brucellosis cases had acute case presentation (73.0%), were males (70.3%), between the ages of 20-60 years (66.2%) and unemployed (89.9%). About two-thirds of cases reported a history of consumption of raw unpasteurized milk. The multivariate analysis revealed that factors associated with the form of brucellosis were age, symptom duration preadmission, fever, antibody titer, and hospitalization outcomes. Conclusion: This study revealed that brucellosis is unevenly distributed across different age groups, as well as regions of Armenia. Affected individuals did not seek medical attention after the onset of the symptoms for about 2 months. Therefore, the targeted educational campaigns could be of crucial importance to prevent the disease in humans, contribute to its early diagnosis and treatment. |
| Databáze: | OpenAIRE |
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