MamuSNP: a resource for Rhesus Macaque (Macaca mulatta) genomics
| Autor: | Dawei Lin, Jessica Satkoski, David Glenn Smith, Ripan S. Malhi, Sreetharan Kanthaswamy, Debbie George, Brad Sickler, Raul Y. Tito |
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| Rok vydání: | 2007 |
| Předmět: |
Genetics and Genomics/Animal Genetics
Quantitative Trait Loci lcsh:Medicine Single-nucleotide polymorphism Genomics Computational biology Quantitative trait locus Macaque Genome Polymorphism Single Nucleotide Gene mapping biology.animal Animals lcsh:Science Molecular Biology Genetics Multidisciplinary biology lcsh:R Genetics and Genomics biology.organism_classification Macaca mulatta Rhesus macaque lcsh:Q Identification (biology) Research Article |
| Zdroj: | PLoS ONE PLoS ONE, Vol 2, Iss 5, p e438 (2007) |
| ISSN: | 1932-6203 |
| Popis: | We developed a novel method for identifying SNPs widely distributed throughout the coding and non-coding regions of a genome. The method uses large-scale parallel pyrosequencing technology in combination with bioinformatics tools. We used this method to generate approximately 23,000 candidate SNPs throughout the Macaca mulatta genome. We estimate that over 60% of the SNPs will be of high frequency and useful for mapping QTLs, genetic management, and studies of individual relatedness, whereas other less frequent SNPs may be useful as population specific markers for ancestry identification. We have created a web resource called MamuSNP to view the SNPs and associated information online. This resource will also be useful for researchers using a wide variety of Macaca species in their research. |
| Databáze: | OpenAIRE |
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