Effect of Right Ventricular Apex Pacing on the Tei Index and Brain Natriuretic Peptide in Patients with a Dual-Chamber Pacemaker

Autor: Chuwa Tei, Tetsuro Kataoka, Shuichi Hamasaki, Yutaka Otsuji, Takuro Shinasato, Yuichi Ninomiya, Tsuyoshi Fukudome, Naoya Oketani, Masakazu Ogawa, Hitoshi Ichiki, Takuro Kubozono, Takehiko Matsushita, Keishi Saihara, Hideki Okui, Sanemasa Ishida
Rok vydání: 2006
Předmět:
Zdroj: Pacing and Clinical Electrophysiology. 29:985-990
ISSN: 1540-8159
0147-8389
DOI: 10.1111/j.1540-8159.2006.00474.x
Popis: Background: Asynchronous electrical activation induced by right ventricular apex (RVA) pacing can cause various abnormalities in left ventricular (LV) function, particularly in the context of severe LV dysfunction or structural heart disease. However, the effect of RVA pacing in patients with normal LV and right ventricular (RV) function has not been fully elucidated. The aim of this study was to characterize the effects of RVA pacing on LV and RV function by assessing isovolumic contraction time and isovolumic relaxation time divided by ejection time (Tei index) and by assessing changes in plasma brain natriuretic peptide (BNP). Methods: Doppler echocardiographic study and BNP measurements were performed at follow-up (mean intervals from pacemaker implantation, 44 ± 75 months) in 76 patients with dual chamber pacemakers (sick sinus syndrome, n = 30; atrioventricular block, n = 46) without structural heart disease. Patients were classified based on frequency of RVA pacing, as determined by 24-hour ambulatory electrocardiogram (ECG) that was recorded just before echocardiographic study: pacing group, n = 46 patients with RVA pacing ≥50% of the time, percentage of ventricular paced 100 ± 2%; sensing group, n = 30, patients with RVA pacing
Databáze: OpenAIRE
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