COVID-19 triggering mucormycosis in a susceptible patient: a new phenomenon in the developing world?
| Autor: | Shweta Mallikarjun Revannavar, Laxminarayana Samaga, Vineeth V K, Supriya P S |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Antifungal Agents Visual acuity 030106 microbiology Diabetes Complications 03 medical and health sciences 0302 clinical medicine Ptosis Amphotericin B Orbital Diseases Paranasal Sinus Diseases Blepharoptosis Humans Mucormycosis Medicine Sinusitis Stroke Sinus (anatomy) Angioinvasion Ophthalmoplegia SARS-CoV-2 business.industry Brain COVID-19 General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Treatment Outcome medicine.anatomical_structure 030221 ophthalmology & optometry Female Radiology medicine.symptom Tomography X-Ray Computed business |
| Zdroj: | BMJ Case Reports. 14:e241663 |
| ISSN: | 1757-790X |
| DOI: | 10.1136/bcr-2021-241663 |
| Popis: | A middle-aged woman with diabetes presented with left-sided facial pain, complete ptosis and fever of short duration. On presentation, she had hyperglycaemia without ketosis. There was total ophthalmoplegia of the left eye with a visual acuity of 6/36. She incidentally tested positive for COVID-19. CT paranasal sinus and MRI brain revealed left-sided pansinusitis with acute infarct in the left parieto-occipital region without angioinvasion. An emergency functional endoscopic sinus procedure was done, which confirmed mucormycosis on histopathological examination. After 1 week of conventional amphotericin B and antibiotics, repeat CT brain showed improvement in mucosal thickening and sinusitis. This case is a rare presentation of mucormycosis associated with rapid progression to orbital apex syndrome with brain infarction in a patient with non-ketotic diabetes and COVID-19. Early diagnosis and treatment are essential to prevent further end-organ damage. It is also interesting that there was no angioinvasion and transient periarterial inflammation was attributed to brain infarction. |
| Databáze: | OpenAIRE |
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