Magnetic resonance diffusion tensor imaging and tractography of the lower spinal cord: application to diastematomyelia and tethered cord
| Autor: | Jay V. Gonyea, Christopher G. Filippi, Keith A. Cauley, Trevor Andrews, Grant J. Linnell |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Male medicine.medical_specialty Cord Fractional anisotropy medicine Humans Radiology Nuclear Medicine and imaging Neural Tube Defects Diastematomyelia Neuroradiology Aged Lumbar Vertebrae business.industry Cauda equina General Medicine Middle Aged medicine.disease Spinal cord medicine.anatomical_structure Diffusion Tensor Imaging Spinal Cord Female Radiology business Tractography Diffusion MRI |
| Zdroj: | European radiology. 20(9) |
| ISSN: | 1432-1084 |
| Popis: | To investigate the feasibility of routine clinical DTI of the lower spinal cord using high-field-strength MRI and parallel imaging, and to evaluate the utility of diffusion tensor imaging and tractography as tools for study of lower cord pathology. Three patients with diastematomyelia, one patient with tethered cord, and six normal volunteers underwent MR imaging of the lower spine at 3 T. A 15-channel spine coil and parallel imaging were used with a six-direction single-shot echo-planar gradient echo technique. In normal volunteers, tractography delineated the conus and cauda equina. Tractography software permitted assessment of fractional anisotropy of the distal cord and nerve roots. In cases of tethered cord, tractography correlated with anatomical imaging. Tractography also correlated with the anatomical pathological findings in cases of diastematomyelia. The methods described enable routine DTI and tractography of the lower spinal cord at 3 T. Compared with conventional imaging, tractography offers additional information that may prove useful in the characterization and surgical planning for congenital lesions involving the lower spinal cord. |
| Databáze: | OpenAIRE |
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