Risk Factors of Aortic Plaque Progression Evaluated by Long-Term Follow-Up Data With Transesophageal Echocardiography
| Autor: | Yusuke Yoshikawa, Kazuaki Kaitani, Hayato Matsutani, Masashi Amano, Shunsuke Nishimura, Kazuyo Kuwano, Yoshihisa Nakagawa, Maiko Kuroda, Toshihiro Tamura, Soichiro Enomoto, Naoaki Onishi, Yusuke Takahashi, Hirokazu Kondo, Sumiyo Hashiwada, Yodo Tamaki, Chisato Izumi, Makoto Miyake |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Longitudinal data Long term follow up Smoking habit Plaque progression Aortic Diseases Aorta Thoracic 030204 cardiovascular system & hematology Severity of Illness Index Coronary artery disease 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Risk Factors Internal medicine medicine Humans In patient Retrospective Studies Creatinine business.industry Warfarin Reproducibility of Results Middle Aged Prognosis medicine.disease Plaque Atherosclerotic chemistry Disease Progression Cardiology Female Cardiology and Cardiovascular Medicine business human activities Echocardiography Transesophageal 030217 neurology & neurosurgery Follow-Up Studies Forecasting medicine.drug |
| Zdroj: | The American Journal of Cardiology. 119:1872-1876 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/j.amjcard.2017.02.036 |
| Popis: | There are few longitudinal data regarding aortic plaque. This study aimed to examine chronological changes in aortic plaques with transesophageal echocardiography (TEE), and to clarify the risk factors of aortic plaque progression. Among 2,675 consecutive patients who underwent TEE, we retrospectively investigated 252 patients who underwent follow-up TEE with an interval >3 years. The thickness and morphology of aortic plaques were examined. Chronological changes in aortic plaques were investigated by comparing baseline and follow-up TEE. Clinical factors, laboratory data, and medications were evaluated. Among 252 study patients, the grade of aortic plaques was unchanged in 213 (group U), but progression was observed in 32 (group P) and regression in 7 patients (group R). Patients in group P were older; they had a higher prevalence of coronary artery disease, hypertension, smoking habit, and moderate or severe plaque at baseline TEE; more patients were using statins and no warfarin; and they had higher creatinine levels than those in group U. In multivariate analysis, moderate or severe plaques at baseline TEE were the strongest predictor of plaque progression. Among 50 patients who showed moderate or severe plaque at baseline TEE, smoking habit and no anticoagulation therapy were predictors of plaque progression. In conclusion, aortic plaques should be followed up using TEE in patients with moderate or severe plaque at baseline TEE. |
| Databáze: | OpenAIRE |
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