A bias away from Th2 in amniotic fluid is involved in preeclampsia

Autor:	Xiaoying Rong, Jie Zhang, Yangyu Zhao, Lixiang Xue, Xiangyang Guo, Mingya Wang, Qian Xiang, Hong Zeng
Rok vydání:	2022
Předmět:	Cesarean Section Tumor Necrosis Factor-alpha Immunology Obstetrics and Gynecology Th1 Cells Amniotic Fluid Th2 Cells Pre-Eclampsia Reproductive Medicine Pregnancy Cytokines Humans Immunology and Allergy Female Interleukin-4 Interleukin-5
Zdroj:	Journal of Reproductive Immunology. 152:103656
ISSN:	0165-0378
Popis:	Inflammatory cytokines contribute to the pathophysiology of preeclampsia. However, whether the imbalance of Th1/Th2 cytokines in amniotic fluid is associated with preeclampsia is not well defined. In the present study, we collected peripheral blood and amniotic fluid from normal pregnancy (n = 25) and preeclampsia (n = 22) at last trimester during cesarean section. The Th1/Th2 cytokine levels in amniotic fluid supernatant were detected by a bead-based immunoassay. The percentage of IFN-γ
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510e0ae653d8aea18fd2f290fd389bc0 https://doi.org/10.1016/j.jri.2022.103656 Zobrazit plný text záznamu Full Text from ScienceDirect