The Measurement of Lipids Currently and 9 Years Ago—Which Is More Associated With Carotid Intima‐Media Thickness?
| Autor: | Liuxin Wu, Yubei Huang, Xuequn Yu, Danielle Millican, Min Lu, Yangfeng Wu, Ping Shi |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Arteriosclerosis Population Clinical Investigations Blood lipids Cohort Studies Internal medicine Total cholesterol Medicine Health Status Indicators Humans education Ultrasonography education.field_of_study business.industry B mode ultrasound Lipid metabolism General Medicine Middle Aged Lipid Metabolism Prognosis Lipids Carotid Arteries Intima-media thickness Cohort Cardiology Disease Progression lipids (amino acids peptides and proteins) Female Cardiology and Cardiovascular Medicine business Tunica Intima Tunica Media Cohort study |
| Popis: | Background: Massive evidence supports that increase of lipids bring more risk of atherosclerosis. However, it is not clear if lipids measured a long time ago bear more risk than the current measurement. Hypothesis: Lipids measured currently is more associated with carotid atherosclerosis than lipids measured long time ago. Methods: A cohort of 1195 participants age 35 to 64 years was examined in both 1993–1994 and 2002 for serum lipids, and in 2002 for carotid intima-media thickness (CIMT) with B mode ultrasound. The associations of lipids at baseline and at reexamination with CIMT were analyzed and compared using multiple linear regressions. Results: All lipid variables, except for high-density lipoprotein cholesterol (HDL-C) both at baseline and reexamination, were significantly associated with age-adjusted CIMT in both males and females (all Ptrend |
| Databáze: | OpenAIRE |
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