Synchronous bilateral Wilms’ tumor with liver metastasis
Autor: | Felix Bongomin, Vincent Mboizi, Senai Goitom Sereke, Abdirahman Omar Sahal |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Male
medicine.medical_specialty Vincristine Palliative care Urology medicine.medical_treatment Case Report Wilms Tumor 030218 nuclear medicine & medical imaging Metastasis 03 medical and health sciences Liver metastases 0302 clinical medicine medicine Bilateral Wilms’ tumor Humans Child Bilateral Wilms Tumor Chemotherapy medicine.diagnostic_test Symptom management business.industry Liver Neoplasms General Medicine Management challenge medicine.disease Diseases of the genitourinary system. Urology Kidney Neoplasms Synchronous medicine.anatomical_structure Reproductive Medicine 030220 oncology & carcinogenesis Abdomen Radiology Renal biopsy RC870-923 business medicine.drug |
Zdroj: | BMC Urology BMC Urology, Vol 21, Iss 1, Pp 1-4 (2021) |
ISSN: | 1471-2490 |
Popis: | BackgroundWilms’ tumor (nephroblastoma) is mostly unilateral; however, bilateral Wilms’ tumors are seen in about 5–8% of patients. This can be synchronous or metachronous. It is uncommon to get liver metastasis from bilateral Wilms’ tumor.Case presentationAn 8-year-old male Ugandan presented with a history of abdominal swelling and flank pains for 1 year. There was no history of hematuria. Both ultrasound and computed tomography of the abdomen demonstrated multiple solid lesions in both kidneys and a huge solid mass in segments V, VI, VII and VIII of the liver. Histological examination of renal biopsy specimen was favorable for chemotherapeutic regimens. However, following a multidisciplinary tumor board consensus, a nephron-sparing surgery was deemed unsuitable, and he was managed conservatively with chemotherapy (adriamycin and vincristine) with a palliative intent.ConclusionsMetastatic bilateral Wilms’ tumor has a particularly poor prognosis. There are no clear evidence-based guidelines for the management of this rare presentation. This patient benefited from early palliative care and symptom management. |
Databáze: | OpenAIRE |
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