Multidimensional daily diary of fatigue-fibromyalgia-17 items (MDF-fibro-17): part 2 psychometric evaluation in fibromyalgia patients
| Autor: | Stephen Morris, W. Wang, J. Cole, S. Dube, C. Burbridge, J. A. M. Smith, Y. Li, T. Symonds, S. Hudgens |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty lcsh:Diseases of the musculoskeletal system Fibromyalgia Psychometrics Sports medicine medicine.medical_treatment Confirmatory factor analysis (CFA) Medical Records Structural equation modeling Validity 03 medical and health sciences 0302 clinical medicine Rheumatology medicine Numeric Rating Scale Humans Orthopedics and Sports Medicine Longitudinal Studies 030212 general & internal medicine Fatigue Reliability (statistics) 030203 arthritis & rheumatology Rehabilitation business.industry Diary Reliability responder Middle Aged MDF-Fibro-17 medicine.disease Quartile Patient reported outcome (PRO) Computers Handheld Physical therapy Female Self Report lcsh:RC925-935 business Research Article |
| Zdroj: | BMC Musculoskeletal Disorders BMC Musculoskeletal Disorders, Vol 18, Iss 1, Pp 1-12 (2017) |
| ISSN: | 1471-2474 |
| DOI: | 10.1186/s12891-017-1545-x |
| Popis: | Background The Multidimensional Daily Diary of Fatigue-Fibromyalgia-17 instrument (MDF-Fibro-17) has been developed for use in fibromyalgia (FM) clinical studies and includes 5 domains: Global Fatigue Experience, Cognitive Fatigue, Physical Fatigue, Motivation, and Impact on Function. Psychometric properties of the MDF-Fibro-17 needed to demonstrate the appropriateness of using this instrument in clinical studies are presented. Methods Psychometric analyses were conducted to evaluate the factor structure, reliability, validity, and responsiveness of the MDF-Fibro-17 using data from a Phase 2 clinical study of FM patients (N = 381). Confirmatory factor analyses (CFA) were performed to ensure understanding of the multidimensional domain structure, and a secondary factor analysis of the domains examined the appropriateness of calculating a total score in addition to domain scores. Longitudinal psychometric analyses (test-retest reliability and responder analysis) were also conducted on the data from Baseline to Week 6. Results The CFA supported the 17-item, 5 domain structure of this instrument as the best fit of the data: comparative fit index (CFI) and non-normed fit index (NNFI) were 0.997 and 0.992 respectively, standardized root mean square residual (SRMR) was 0.010 and the root mean square error of approximation (RMSEA) was 0.06. In addition, total score (CFI and NNFI both 0.95) met required standards. For the total and 5 domain scores, reliability and validity data were acceptable: test-retest and internal consistency were above 0.9; correlations were as expected with the Global Fatigue Index (GFI) (0.62-0.75), Fibromyalgia Impact Questionnaire (FIQ) Total (0.59–0.71), and 36-Item Short Form Health Survey (SF-36) vitality (VT) (0.43–0.53); and discrimination was shown using quintile scores for the GFI, FIQ Total, and Pain Numeric Rating Scale (NRS) quartiles. In addition, sensitivity to change was demonstrated with an overall mean responder score of -2.59 using anchor-based methods. Conclusion The MDF-Fibro-17 reliably measures 5 domains of FM-related fatigue and psychometric evaluation confirms that this measure meets or exceeds each of the predefined acceptable thresholds for evidence of reliability, validity, and responsiveness to changes in clinical status. This suggests that the MDF-Fibro-17 is an appropriate and responsive measure of FM-related fatigue in clinical studies. |
| Databáze: | OpenAIRE |
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