Peripheral Oxidative Stress Blood Markers in Patients With Chronic Back or Neck Pain Treated With High-Velocity, Low-Amplitude Manipulation
| Autor: | Ana Paula Konzen Riffel, Felipe Coutinho Kullmann Duarte, Taina Scheid, Wania Aparecida Partata, Maira Silmara de Moraes, Andréa Horst, Angela Kolberg, Carolina Kolberg |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Manipulation Spinal Antioxidant Enzymes medicine.medical_specialty Spinal Nitric Oxide Spinal manipulation medicine.disease_cause Severity of Illness Index Gastroenterology Cohort Studies Superoxide dismutase Internal medicine medicine Back pain Humans Manipulation chemistry.chemical_classification Neck pain Neck Pain biology Manipulation Chiropractic Superoxide Dismutase business.industry Glutathione peroxidase Chronic pain Middle Aged Catalase Chiropractic medicine.disease Surgery Manual Therapy Oxidative Stress Treatment Outcome chemistry biology.protein Female Chiropractics Chronic Pain medicine.symptom business Low Back Pain Biomarkers Brazil Oxidative stress |
| Zdroj: | Journal of Manipulative and Physiological Therapeutics. 38:119-129 |
| ISSN: | 0161-4754 |
| Popis: | ObjectiveThe purpose of this study was to investigate oxidative-stress parameters in individuals with chronic neck or back pain after 5 weeks of treatment with high-velocity, low-amplitude (HVLA) spinal manipulation.MethodsTwenty-three individuals aged 38.2 ± 11.7 years with nonspecific chronic neck or back pain verified by the Brazilian Portuguese version of the Chronic Pain Grade, with a sedentary lifestyle, no comorbidities, and not in adjuvant therapy, underwent treatment with HVLA chiropractic manipulation twice weekly for 5 weeks. Therapeutic procedures were carried out by an experienced chiropractor. Blood samples were assessed before and after treatment to determine the activities of the antioxidant enzymes superoxide dismutase (SOD), catalase and glutathione peroxidase (GPx), and the levels of nitric oxide metabolites and lipid hydroperoxides. These blood markers were analyzed by paired Student t test. Differences were considered statistically significant, when P was |
| Databáze: | OpenAIRE |
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