Erythromycin therapy in bullous pemphigoid: possible anti-inflammatory effects
| Autor: | Barbara J. Fox, Richard B. Odom, Robert F. Findlay |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Drug
medicine.medical_specialty medicine.drug_class Systemic steroid media_common.quotation_subject Anti-Inflammatory Agents Erythromycin Fluorescent Antibody Technique Dermatology Disease Anti-inflammatory Pemphigoid Bullous Medicine Humans media_common Aged Skin Diseases Vesiculobullous business.industry medicine.disease Child Preschool Immunoglobulin G Female Bullous pemphigoid business medicine.drug |
| Zdroj: | Journal of the American Academy of Dermatology. 7(4) |
| ISSN: | 0190-9622 |
| Popis: | Two patients with bullous pemphigoid treated with erythromycin demonstrated improvement. This response suggests that erythromycin may be a fairly safe supplemental drug which may allow a lower dose of systemic steroid, or may be of benefit when used alone or in combination with topical steroids in treating patients who are not ideal candidates for a systemic steroid. Erythromycin appears to have a significant anti-inflammatory effect, and possible mechanisms for this effect are proposed. One of the patients was a 4th-year-old girl whose disease manifested several unusual features, making diagnosis difficult. A brief summary of differential immunofluorescent findings in childhood bullous diseases is also presented. (J AM ACAD DERMATOL 7:504-510, 1982.) |
| Databáze: | OpenAIRE |
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