In vivo cross-sectional imaging of the phonating larynx using long-range Doppler optical coherence tomography
| Autor: | Swathi Rangarajan, Zhongping Chen, Giriraj K. Sharma, Joseph C. Jing, Jason J. Chen, Brian J. F. Wong, Carolyn A. Coughlan, Kyoungrai Cho, Julie A. Goddard, Lidek Chou, Theodore H. Chang, Donghoon Lee |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Larynx
Speech recognition Laryngoscopy Vocal Cords 01 natural sciences Stroboscope Article 010309 optics 03 medical and health sciences 0302 clinical medicine Optical coherence tomography 0103 physical sciences medicine Vocal cord dysfunction Humans Phonation 030223 otorhinolaryngology Multidisciplinary medicine.diagnostic_test business.industry medicine.disease medicine.anatomical_structure Vocal Cord Dysfunction Vocal folds Tomography business Tomography Optical Coherence Biomedical engineering |
| Zdroj: | Scientific Reports |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/srep22792 |
| Popis: | Diagnosis and treatment of vocal fold lesions has been a long-evolving science for the otolaryngologist. Contemporary practice requires biopsy of a glottal lesion in the operating room under general anesthesia for diagnosis. Current in-office technology is limited to visualizing the surface of the vocal folds with fiber-optic or rigid endoscopy and using stroboscopic or high-speed video to infer information about submucosal processes. Previous efforts using optical coherence tomography (OCT) have been limited by small working distances and imaging ranges. Here we report the first full field, high-speed, and long-range OCT images of awake patients’ vocal folds as well as cross-sectional video and Doppler analysis of their vocal fold motions during phonation. These vertical-cavity surface-emitting laser source (VCSEL) OCT images offer depth resolved, high-resolution, high-speed, and panoramic images of both the true and false vocal folds. This technology has the potential to revolutionize in-office imaging of the larynx. |
| Databáze: | OpenAIRE |
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