Plaque inhibition by guanidino propyl piperazine (CKO 569A)
| Autor: | Gunnar Rölla, Ellen Zeuner, Nina Agerbæk, Birte Melsen |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Adult
Male endocrine system Adolescent Chemical Phenomena Dental Plaque Dentistry Pharmacology Placebo Guanidines Piperazines Clinical study Placebos Random Allocation medicine Humans General Dentistry Clinical Trials as Topic Chemistry business.industry Chlorhexidine Oral Hygiene Guanidino propyl piperazine Plaque inhibition Female business medicine.drug |
| Zdroj: | Scandinavian journal of dental research. 88(3) |
| ISSN: | 0029-845X |
| Popis: | – The plaque inhibiting effect of the antibacterial substance, guanidino propyl piperazine (CKO 569A) has been analyzed in a clinical study of 10 adults. Plaque formation was enhanced by three daily rinses with 15% sucrose. Normal hygiene was performed. The effects of a twice daily mouthwash of 30 s duration with 0.2, 0.1 and 0.05% CKO 569A, 0.05% chlorhexidine and a placebo on plaque formation were compared through a registration of plaque scores. Each solution was tested over a period of 5 days. As a result of this study it could be concluded that in humans CKO 569A is an effective inhibitor of plaque, and that lingual plaque scores appear to be a good indicator of plaque inhibiting activity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text