The relationship between the transfer factor obtained at rest, and arterial oxygen tension during exercise, in patients with miscellaneous pulmonary diseases
| Autor: | K. Nemcek, U. Arvidsson, L. Fransson, S. J. Andersen, S.‐E. Svensson |
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| Rok vydání: | 1992 |
| Předmět: |
Adult
Male medicine.medical_specialty Rest Physical Exertion Transfer Factor Physical exercise Pulmonary function testing Hypoxemia Predictive Value of Tests Fibrosis Internal medicine Pulmonary fibrosis Internal Medicine medicine Humans Lung Diseases Obstructive Aged Sweden Lung business.industry Respiratory disease Middle Aged medicine.disease Surgery Dyspnea medicine.anatomical_structure Evaluation Studies as Topic Exercise Test Cardiology Arterial blood Female Blood Gas Analysis medicine.symptom Lung Volume Measurements business |
| Zdroj: | Journal of Internal Medicine. 232:415-419 |
| ISSN: | 1365-2796 0954-6820 |
| DOI: | 10.1111/j.1365-2796.1992.tb00607.x |
| Popis: | Forty-one consecutive patients with the symptom ‘exertional dyspnoea’ were referred to the Department of Clinical Physiology for evaluation. Pulmonary fibrosis and chronic obstructive pulmonary disease were the most common diagnoses but other diagnoses were also represented. Some patients had no clinical diagnosis or radiological signs. All patients underwent exercise testing with sampling of arterial blood for blood gas analysis and pulmonary function testing including measurement of the transfer factor (carbon monoxide diffusing capacity) at rest. Independent of spirometric findings and diagnosis a significant correlation (r = 0.80. P < 0.001) was shown to exist between the transfer factor measured at rest and the arterial oxygen tension at maximal exercise level. We recommend measurement of the transfer factor as a screening test for exertional hypoxaemia and suggest that exercise blood gas analysis only seems necessary in patients with a transfer factor between 55% and 80% of the predicted value. |
| Databáze: | OpenAIRE |
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