Systematic review on the value of end-of-treatment FDG-PET in improving overall survival of lymphoma patients
| Autor: | Hugo J. A. Adams, Thomas C. Kwee |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
Oncology medicine.medical_specialty Lymphoma MEDLINE Review Article DIAGNOSIS Disease-Free Survival law.invention Cohort Studies Randomized controlled trial Fluorodeoxyglucose F18 law Response assessment HODGKIN-LYMPHOMA Internal medicine Overall survival Humans Medicine BENEFIT B-cell lymphoma FDG-PET Hematology medicine.diagnostic_test business.industry INTERIM B-CELL LYMPHOMA 1ST REMISSION General Medicine medicine.disease Survival Rate carbohydrates (lipids) PROGNOSTIC VALUE Positron emission tomography Positron-Emission Tomography Cohort Female Therapy CLINICAL-PRACTICE GUIDELINES business End-of-treatment |
| Zdroj: | Annals of Hematology |
| ISSN: | 0939-5555 |
| Popis: | This study aimed to systematically review the value of end-of-treatment 18F-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) in improving overall survival (OS) of lymphoma patients. Medline was systematically searched for (1) randomized trials comparing the OS of patients who underwent end-of-treatment FDG-PET to those without and FDG-PET-based end-of-treatment evaluation and for (2) non-randomized studies comparing the OS of patients who underwent end-of-treatment FDG-PET to a (historical) cohort of patients without an FDG-PET-based end-of-treatment evaluation. The Medline search revealed 6284 articles. However, none of these reported data on the value of end-of-treatment FDG-PET in improving OS of lymphoma patients. In conclusion, the present systematic review reveals that there is currently no study at all that evaluates the value of end-of-treatment FDG-PET in improving OS of lymphoma patients. As a result, it remains unknown whether end-of-treatment FDG-PET increases OS and in which lymphoma subtype these examinations are of particular value. Future studies are required to demonstrate its value in this setting before it can be recommended as an evidence-based diagnostic tool by guidelines on the use of imaging in lymphoma. |
| Databáze: | OpenAIRE |
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